Factor XIII symposium and standardization working group meeting at the 50th GTH meeting in Basel


Important Information!!

As to the registration for Factor XIII symposium, Prof. Laemmle, the president of the 50th GTH meeting, kindly offered us the following conditions;

1) all persons attending exclusively the Factor XIII symposium (speakers and possible individual attendants) will have free admission, thus there will be no registration fee.

2) those attendants who stay for the whole day have to register and pay 100 Euro (we cannot give one-day registrations at reduced rates).



Prof. Akitada Ichinose (Yamagata University, Japan),

Prof. Rainer Seitz (Paul-Ehrlich-Institut, Germany)


Time: 09:00-12:00 February 15, 2006

Venue: Kongresszentrum Basel

Room: RIO



1) FXIII deficient mice developed cardiac fibrosis. by Prof. Akitada Ichinose (Yamagata University, Japan)

2) Impact of FXIII on healing after myocardial infarction. by Dr. Matthias Nahrendorf (Harvard Medical School, USA)

3) Effect of Factor XIII (FXIII) on migration, proliferation and apoptosis of monocytes, smooth muscle cells and fibroblasts. by Dr. Aida Inbal (Tel Aviv University, Israel)

4) Down-regulation of factor XIII within the fibrin clot. by Dr. Zsuzsa Bagoly and Prof. Laszlo Muszbek (Debrecen University, Hungary)

5) Interaction sites of FXIII for fibrin(ogen) using recombinantly expressed domains. by Dr. Robert Ariens (Leeds University, UK)

6) Determination of Coagulation FXIII in Blood Products using a Novel Fluorescent Isopeptidase Assay. by Dr. Johannes Dodt and Prof. Rainer Seitz (Paul-Ehrlich-Institut, Germany)

7) Problems relating to the laboratory diagnosis of suspected factor XIII deficiency. by Prof. Hans P. Kohler (University of Bern, Switzerland)

8) An Update on the Standardization of FXIII Studies (on FXIII Plasma Ag assignment & Protocols for the Concentrate Pilot as well as IS Study). by Dr. Sanj Raut (NIBSC, UK)

9) Proposal of International Collaborative study for Standard factor XIII Concentrates and recombinant factor XIII product. by Prof. Akitada Ichinose (Yamagata University, Japan)

10) Invitation to the factor XIII subcommittee at the 52nd Annual SSC Meeting, June 28-July 1, 2006, Oslo, Norway. by Prof. Rainer Seitz (PEI, Germany)


Symposium at the 49th GTH meetings in Mannheim

Factor XIII Symposium & Workshop on FXIII Standardization


Date: Wednesday, February 23, 2005, 09:00 to 13:00,

Venue: "Konferenzsaal EG", Congress Center Rosengarten, Mannheim, Germany

Chair persons: A. Ichinose (Yamagata University, Japan) and R. Seitz (Paul-Ehrlich-Institut, Langen, Germany)


Scientific Session:

09:00-09:15 Dr. Ichinose: Transglutaminase-related Diseases

09:15-09:30 Dr. Kohler: "Historical Sketch: Congenital FXIII deficiency"

09:30-09:45 Drs. Oldenburg and Ivaskevicius: Progress in an extended registry of XIII deficiency

09:45-10:00 Dr. Muszbek: Acquired factor XIII deficiencies; severe factor XIII deficiency caused by an autoantibody against the B subunit

10:00-10:15 Dr. Wolfgang Korte: Factor XIII levels and unexpected intraoperative bleeding

10:15-10:30 Dr. Ariens: SNPs in Factor XIII genes and disease states

10:30-10:45 Dr. Olaf Kilan: Factor XIII induces microvessel ingrowth into hydroxyapatite implants

10:45-11:00 Dr. Aida Inbal: Role of FXIII in wound repair; revisited

11:00-11:15 Dr. Adany: Possible roles of the intracellular FXIII A

11:15-11:35 Dr. Ursula Quitterer: Stabilization of angiotensin II AT1 receptor dimers by factor XIIIA


Short break: 11:35-11:45


Workshop of XIIISWG:

11:45-12:00 Dr. Muszbek: Standardization of Factor XIII Antigen Assay

12:00-12:15 Drs. Barrowcliffe and Raut: Review of international standard materials using concentrates and recombinant proteins

12:15-12:30 Dr. Seitz: Standardization of Factor XIII Concentrate; to be or not to be?

12:30-12:45 Dr. Metzner: Making of Factor XIII concentrates and fibrin sealants


Discussion: 12:45-13:00