荒木 明美(ARAKI Akemi)

  基礎棟最上階(5F)からの四季折々の美しい景色を眺めながら、毎日清々しい気持ちで勤務しております。日々刻々と成長し続ける木々たちには、頭が下がります。これまでしばらく勉学を怠けてきたことを反省しつつ、少しでも世の流れに付いていこうと修業しているところです。
最近の生命科学研究においては、分野ごとの垣根がなくなってきているような気がします。研究室間でもっと交流があればお互いにもっと発展できるのではと思いますので、大いに遊びにお出でください。コーヒー党の人が多いので、教室にはいつも美味しいコーヒーとお菓子を常備しております。

主要業績
Suzuki, K., Watanabe, T., Sakurai, S., Ohtake, K., Konoshita, T., Araki, A., Fujita, T., Takei, H., Takeda, Y., Sato, Y., Yamashita, T., Araki, Y., and Sendo, F. : Regulation of neutrophil extravasation by a novel glycosylphosphatidyl inositol (GPI)-anchored protein on leukocytes.  J. Immunol., 162, 4277-4284, 1999.

Uchida, T., Yamashita, T., Araki, A., Watanabe, H., and Sendo, F. : rIFN-γ-activated rat neutrophils induce tumor cell apoptosis by nitric oxide.  Int. J. Cancer, 71, 231-236, 1997.

Yamashita, T., Uchida, T., Araki, A., and Sendo, F. : Nitric oxide is an effector molecule in inhibition of tumor cell growth by rIFN-γ-activated rat neutrophils.  Int. J. Cancer, 71, 223-230, 1997.

Sato, T., Midorikawa, Y., Yamashita, T., Araki, A., and Sendo, F. : The neutrophil as an information transmitter in tumor inhibition by a streptococcal biological response modifier, OK-432.  Cancer Immunol. Immunother., 43, 77-86, 1996.

Araki, A., and Sedno, F. : Reduced anti-Pseudomonas Aeruginosa activity of a cephalosporin, cefodizime, in rats whose neutrophils were selectively depleted by a monoclonal antibody.  Microbiol. Immunol., 40, 333-338, 1996.

Takei, H., Araki, A., Watanabe, H., Ichinose, A, and Sendo, F. : Rapid killing of human neutrophils by the potent activator phorbol 12-myristate 13-acetate (PMA) accompanied by changes different from typical apoptosis or necrosis.  J. Leukoc. Biol., 59, 229-240, 1996.

Kudo, C., Yamashita, T., Araki, A., Terashita, M., Watanabe, T., Atsumi, M., Tamura, M., and Sendo, F. : Modulation of the in vivo immune response by selective depletion of neutrophils using a monoclonal antibody, RP-3.  I. Inhibition by RP-3 treatment of the priming and effector phases of delayed type hypersensitivity to sheep red blood cells in rats.  J. Immunol., 150, 3728-3738, 1993.

Kudo, C., Araki, A., Matsushima, K., and Sendo, F. : Inhibition of IL-8-induced W3/25+ (CD4+) T Iymphocyte recruitment into subcutaneous tissues of rats by selective depletion of in vivo neutrophils with a monoclonal antibody.  J. Immunol., 147, 2196-2201, 1991.

Araki, A., Inoue, T., Cragoe, E. J. Jr., and Sendo, F. : Na+/H+ exchange modulates rat neutrophil mediated tumor cytotoxicity.  Cancer Res., 51, 3212-3216, 1991.

Araki, A., Inoue, T., Kimura, S., Fukase, S., and Sendo, F. : Enhancement of polymorphonuclear leukocyte-mediated tumor cytotoxicity by serum factor(s).  Jpn. J. Cancer Res., 81, 69-78, 1990.

Inoue, T., Hamuro, J., Yoshimoto, R., Okano, A., Shitara, A., Arai, S., and Sendo, F. : A Tcell leukemia line produces factor(s) that render rat neutrophils cytotoxic.  Jpn. J. Cancer Res., 77, 693-702, 1986.