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Original Papers | Reviews and Proceeding | 【和文総説、他】 |
【1999年〜2017の教室業績】 
赤字は研究実施当時大学院生、教室員アンダーラインで示す
※1999年以前もしくは着任前の各スタッフ業績については個人ファイルをご覧ください。

 Original Papers


【2017】
 146. Jaeyong Lee, Eun Sil Kang, Sho Kobayashi, Takujiro Homma, Hideyo Sato, Han Geuk Seo, Junichi Fujii
The viability of primary hepatocytes is maintained under a low cysteine-glutathione redox state with a marked elevation in ophthalmic acid production.
Exp Cell Res, in press (2017)
145. Shinji Hamashima, Takujiro Homma, Sho Kobayashi, Naoki Ishii, Toshihiro Kurahashi, Ren Watanabe, Naoko Kimura, Hideyo Sato, Junichi Fujii.
Decreased reproductive performance in xCT-knockout male mice.
Free Radic Res, in press (2017) doi: 10.1080/10715762.2017.1388504
144. Sho Kobayashi, Jaeyong Lee, Toshifumi Takao, Junichi Fujii.
Increased ophthalmic acid production is supported by amino acid catabolism under fasting conditions in mice.
 
Biochem Biophys Res Commun. 491:649-655 (2017) doi: 10.1016/j.bbrc.2017.07.149. 
143. Jaeyong Lee, Takujiro Homma, Junichi Fujii.
Mice in the early stage of liver steatosis caused by a high fat diet are resistant to thioacetamide-induced hepatotoxicity and oxidative stress.
Toxicol Lett, 277:92-103 (2017) doi:10.1016/j.toxlet.2017.06.005.   
142. Eun Sil Kang, Jaeyong Lee, Takujiro Homma, Toshihiro Kurahashi, Sho Kobayashi, Atsunori Nabeshima, Sohsuke Yamada, Han Geuk Seo, Satoshi Miyata, Hideyo Sato, Junichi Fujii
xCT deficiency aggravates acetaminophen-induced hepatotoxicity under inhibition of the transsulfuration pathway

Free Radic Res, 51, 80-90 (2017)  doi: 10.1080/10715762.2017.1282157 
141. Eisuke Tasaka, Shotaro Matsumoto, Hisashi Tada, Toshihiro Kurahashi, Xuhong Zhang, Junichi Fujii, Toshihiko Utsumi, Yoshihito Iuchi.
Protective role of testis-specific peroxiredoxin 4 against cellular oxidative stress. 
J Clin Biochem Nutr, 60:156-161 (2017) doi: 10.3164/jcbn.
 140. Takaya Shirato, Takujiro Homma, Jaeyong Lee, Toshihiro Kurahashi, Junichi Fujii.
Oxidative stress caused by a SOD1 deficiency ameliorates thioacetamide-triggered cell death via CYP2E1 inhibition but stimulates liver steatosis.
Arch Toxicol, 91:1319-1333 (2017) doi: 10.1016/j.abb.2016.06.004.  
139. Eduard Bentea, Joeri Van Liefferinge, Lise Verbruggen, Katleen Martens, Sho Kobayashi, Lauren Deneyer, ThomasDemuyser, Giulia Albertini, Katrien Maes, Hideyo Sato, Ilse Smolders, Jan Lewerenz, Ann Massie.
Zonisamide attenuates lactacystin-induced parkinsonism in mice withoutaffecting system xc−.
Exp Neurol, 290, 15-28 (2017) doi: 10.1016/j.expneurol.2016.12.009. 
138. Sebastian Doll, Bettina Proneth, Yulia Y Tyurina, Elena Panzilius, Sho Kobayashi, Irina Ingold, Martin Irmler, Johannes Beckers, Michaela Aichler, Axel Walch, Holger Prokisch, Dietrich Trumbach, Gaowei Mao, Feng Qu, Hulya Bayir, Joachim Fullekrug, Christine H Scheel, Wolfgang Wurst, Joel A Schick, Valerian E Kagan, Jose Pedro Friedmann Angeli, and Marcus Conrad.
ACSL4 Dictates Ferroptosis Sensitivity by Shaping Cellular Lipid Composition.
Nat Chem Biol, 13(1):91-98 (2017) doi: 10.1038/nchembio.2239. 
137. Takujiro Homma, Ryusuke Akihara, Satoshi Okano, Mototada Shichiri, Yasukazu Yoshida, Ken-ichi Yamada, Satoshi Miyata, Osamu Nakajima, Junichi Fujii.
Heightened aggressive behavior in mice deficient in aldo-keto reductase 1a (Akr1a).
Behav Brain Res, 319:219-224 (2017) doi: 10.1016/j.bbr.2016.11.038. 
136. Junitsu  Ito, Naoki  Ishii, Ryusuke  Akihara, Jaeyong  LeeToshihiro  Kurahashi, Takujiro  Homma, Ryo  Kawasaki,Junichi Fujii.
A high fat diet temporarily renders Sod1-deficient mice resistant to an oxidative insult.
J Nutr Biochem, 40:44-52 (2017) doi: 10.1016/j.jnutbio.2016.10.018.
【2016】  
 135. Takujiro Homma, Junichi Fujii.
Heat stress promotes the down-regulation of IRE1α in cells: An atypical modulation of the UPR pathway.
Exp Cell Res, 349:128-138 (2016) doi: 10.1016/j.yexcr.2016.10.006.  
134. Ryusuke Akihara, Takujiro Homma, Jaeyong Lee, Ken-ichi Yamada, Satoshi Miyata, Junichi Fujii.
Ablation of aldehyde reductase aggravates carbon tetrachloride-induced acute hepatic injury involving oxidative stress and endoplasmic reticulum stress
Biochem Biophys Res Commun. 478:765-771 (2016) doi: 10.1016/j.bbrc.2016.08.022.
133. Toshihiro Kurahashi, Jaeyong Lee, Atsunori Nabeshima, Takujiro Homma, Eun Sil Kang, Yuka Saito, Sohsuke Yamada, Toshiyuki Nakayama, Ken-ichi Yamada, Satoshi Miyata, Junichi Fujii.
Ascorbic acid prevents acetaminophen-induced hepatotoxicity in mice by ameliorating glutathione recovery and autophagy.
Arch Biochem Biophys, 604:36-46 (2016)  doi: 10.1016/j.abb.2016.06.004.
132. Noriyuki Otsuki, Takujiro Homma, Hiroki Fujiwara, Kenya Kaneko, Yasukazu Hozumi, Mototada Shichiri, Mizuki Takashima, Junitsu Ito, Tasuku Konno, Toshihiro Kurahashi, Yasukazu Yoshida, Kaoru Goto, Satoshi Fujii,Junichi Fujii.
Trichloroethylene exposure aggravates behavioral abnormalities in mice that are deficient in superoxide dismutase.
Regul Toxicol Pharmacol. 79:83-90 (2016) doi: 10.1016/j.yrtph.2016.05.007.  
131. Noriyuki Otsuki, Tasuku Konno, Toshihiro Kurahashi, Saori Suzuki, Jaeyong Lee, Futoshi Okada, Yoshihito Iuchi, Takujiro Homma, Junichi Fujii,
The SOD1 transgene expressed in erythroid cells alleviates fatal phenotype in congenic NZB/NZW-F1 mice.
Free Radic Res, 50(7):793-800 (2016) doi: 10.1080/10715762.2016.1178388.
 130. Eliska Holzerova, Katharina Danhauser, Tobias B. Haack, Laura S Kremer, Marlen Melche, Irina Ingold, Sho Kobayashi, Caterina Terrile, Petra Wolf, Jorg Schaper, Ertan Mayatepek, Fabian Baertling, Jose Pedro Friedmann Angeli, Marcus Conrad, Tim M Strom, Thomas Meitinger, Prokisch Holge, and Felix Distelmaie.
Human thioredoxin 2 deficiency impairs mitochondrial redox homeostasis and causes early-onset neurodegeneration.  

Brain
, 139, 346-354 (2016) doi: 10.1093/brain/awv350.
129. Aya Nawata, Hirotsugu Noguchi, Yuichi Mazaki, Toshihiro Kurahashi, Atsunori Nabeshima, Ke-Yong Wang, Satoshi Kimura, Hidetaka Uramoto, Kimitoshi Kohno, Hatsumi Taniguchi, Yoshiya Tanaka, Junichi Fujii, Yasuyuki Sasaguri Toshiyuki Nakayama, and Sohsuke Yamada.
Overexpression of Peroxiredoxin 4 Induces Adaptive Intestinal Lipid Metabolism Associated with Suppressive Nonalcoholic Steatohepatitis in a Dietary Mouse Model.
PLoS One, 11: e0152549 (2016) doi: 10.1371/journal.pone.0152549.  
128. Hiroshi Nagahisa, Kazuma Okabe, Yoshihito Iuchi, Junichi Fujii, Hirofumi Miyata.
Characteristics of skeletal muscle fibers of SOD1 knockout mice.
Oxid Med Cell Longev. 9345970 (2016) doi: 10.1155/2016/9345970 
【2015】  
127. Tasuku Konno, Eduardo Pinho Melo, Carlos Lopes, Ilir Mehmeti, Sigurd Lenzen, Davi dRon, and Edward Avezov.
ERO1-independent production of H2O2 within the endoplasmic reticulum fuels Prdx4-mediated oxidative protein folding
J Cell Biol 211:253-259 (2015)  
126. Toshihiro Kurahashi, Shinji Hamashima, Takaya Shirato, Jaeyong Lee, Takujiro Homma, Eun Sil Kang, Junichi Fujii.
An SOD1 deficiency enhances lipid droplet accumulation in the fasted mouse liver by aborting lipophagy

Biochem Biophys Res Commun, 467:866-871 (2015) 
125. Daisuke Ishibashi, Takujiro Homma, Takehiro Nakagaki, Takayuki Fuse, Kazunori Sano, Hanae Takatsuki, Ryuichiro Atarashi, Noriyuki Nishida.
Strain-Dependent Effect of Macroautophagy on Abnormally Folded Prion Protein Degradation in Infected Neuronal Cells.
PLoS One. 2015 Sep 14;10(9):e0137958. doi: 10.1371/journal.pone.0137958. 
124.

Takujiro Homma, Toshihiro Kurahashi, Jaeyong Lee, Eun Sil Kang and Junichi Fujii
SOD1 deficiency decreases proteasomal function, leading to the accumulation of ubiquitinated proteins in erythrocytes.
Arch Biochem Biophys, 583:65-72 (2015) 

123. Jaeyong Lee, Takujiro Homma, Toshihiro Kurahashi, Eun Sil Kang, and Junichi Fujii.
Oxidative stress triggers lipid droplet accumulation in primary cultured hepatocytes by activating fatty acid synthesis.

Biochem Biophys Res Commun
, 464:229-235 (2015)  
122. Takujiro Homma, Satoshi Okano, Jaeyong Lee, Junitsu Ito, Noriyuki Otsuki, Toshihiro Kurahashi, Eun Sil Kang, Osamu Nakajima, and Junichi Fujii.
SOD1 deficiency induces the systemic hyperoxidation of peroxiredoxin in the mouse.
Biochem Biophys Res Commun
, 463:1040-1046 (2015)  
121. Takujiro Homma, Daisuke Ishibashi, Takehiro Nakagaki, Takayuki Fuse, Tsuyoshi Mori, Katsuya Satoh, Ryuichiro Atarashi, and Noriyuki Nishida. Ubiquitin-specific protease 14 modulates degradation of cellular prion protein.
Sci. Re
p.
5:11028 (2015) 
 
120. Ye Yan, Cynthia Wladyka, Junichi Fujii, and Shanthini Sockanathan.
Prdx4 is a compartment-specific H
2O2 sensor that regulates neurogenesis by controlling surface expression of GDE2.
Nat Commun, 6:7006 (2015)  
 119.  Sho Kobayashi, Mami Sato, Takayuki Kasakoshi, Takumi Tsutsui, Masahiro Sugimoto, Mitsuhiko Osaki, Futoshi Okada, Kiharu Igarashi,Jun Hiratake, Takujiro Homma, Marcus Conrad, Junichi Fujii, Tomoyoshi Soga, Shiro Bannai, and Hideyo Sato.
Cystathionine is a novel substrate ofcystine/glutamate transporter: implications forimmune function.
J Biol Chem, 290(14):8778-8788 (2015) 
 118. Avezov E, Konno T, Zyryanova A, Chen W, Laine R, Crespillo-Casado A, Melo E, Ushida R, Nagata K, Kaminski CF, Harding HP, and Ron D
Retarded PDI diffusion and a redutive shift in poise of the calcium depleted endoplasmic reticulum.
BMC Biol. 13: 2 (2015)
【2014】  
117.

Tsunoda S, Avezov E, Zyryanova A, Konno T, Mendes-Silva L, Pinho Melo E, Harding HP, and Ron D.
Intact protein folding in the glutathione-depleted endoplasmic reticulum implicates alternative protein thiol reductants.
Elife
. 3: e03421 (2014) 

116. Toshihiro Kurahashi, Myoungsu Kwon, Takujiro Homma, Yuka Saito, Jaeyong Lee, Motoko Takahashi, Ken-ichi Yamada, Satoshi Miyata, and Junichi Fujii.
Reductive detoxification of acrolein as a potential role for aldehyde reductase (AKR1A) in mammals.  
Biochem Biophys Res Commun, 452:136-141 (2014) 
115. Takujiro Homma, Daisuke Ishibashi, Takehiro Nakagaki, Takayuki Fuse, Kazunori Sano, Katsuya Satoh, Ryuichiro Atarashi, Noriyuki Nishida.
Persistent prion infection disturbs the function of Oct-1, resulting in the down-regulation of murine interferon regulatory factor-3.
Sci. Rep. 4:6006 (2014)
114. Takujiro Homma, Daisuke Ishibashi, Takehiro Nakagaki, Katsuya Satoh, Kazunori Sano, Ryuichiro Atarashi, Noriyuki Nishida.
Increased expression of p62/Sequestosome-1 in prion diseases and its association with pathogenic prion protein.
Sci Rep. 4:4504 (2014) 
 113. Nishida H, Kurahashi T, Saito Y, Otsuki N, Kwon M, Ohtake H, Yamakawa M, Yamada K, Miyata S, Tomita Y, and Fujii J.
Kidney fibrosis is independent of the amount of ascorbic acid in mice with unilateral ureteral obstruction.
Free Radic Res, 48(9):1115-1124 (2014)
112. Ito J, Otsuki N, Zhang X, Konno K, Kurahashi T, Takahashi M, Yamato M, Matsuoka Y, Yamada K, Miyata S, and Fujii J.
Ascorbic acid reverses the prolonged anesthetic action of pentobarbital in Akr1a-knockout mice.
Life Sciences, 95:1-8 (2014) 
【2013】  
 111. Konno T, Otsuki N, Kurahashi T, Kibe N, Tsunoda S, Iuchi Y, and Fujii J.
Reactive oxygen species exacerbate autoimmune hemolytic anemia in New Zealand black mice.
Free Radic. Biol. Med. 65:1378-1384 (2013)
110. Fukuda N, Ito T, Ohwada K, and Fujii J.
Upregulation of fatty acid synthesis and the suppression of hepatic triglyceride lipase as a direct cause of hereditary postprandial hypertriglyceridemia in rabbits.
J. Clin. Biochem. Nutr. 53(2) 114-121 (2013)  
109. Tsunoda S, Kibe N, Kurahashi T, and Fujii J.
Differential responses of SOD1-deficient mouse embryonic fibroblasts to oxygen concentrations.
Arch. Biochem. Biophys. 537(1):5-11 (2013)
108. Nabeshima A, Yamada S, Guo X, Tanimoto A, Wang KY, Shimajiri S, Kimura S, Tasaki T, Noguchi H, Kitada S, Watanabe T, Fujii J, Kohno K, and Sasaguri Y.
Peroxiredoxin 4 Protects Against Nonalcoholic Steatohepatitis and Type 2 Diabetes in a Nongenetic Mouse Model
Antioxid. Redox Signal 19(17):1983-1998 (2013) 
【2012】  
107.

Kobayashi S, Kuwata K, Sugimoto T, Igarashi K, Osaki M, Okada F, Fujii J, Bannai S, and Sato H.
Enhanced expression of cystine/glutamate transporter in the lung caused by the oxidative stress-inducing agent paraquat
Free Radic Biol Med, 53:2197-2203 (2012) 

106. Kurahashi T, Konno T, Otsuki N, Kwon M, Tsunoda S, Ito J, Fujii J.
A malfunction in the triglyceride transfer from the intracellular lipid pool to the apoB in the enterocytes of SOD1-deficient mice.

FEBS Lett
, 586:4289-4295(2012)
105. Zito E, Hansen HG, Yeo GSH, Fujii J, Ron D.
Endoplasmic reticulum thiol oxidase deficiency leads to ascorbic acid depletion and noncanonical scurvy in mice. 
Mol Cell, 48:39-51(2012) 
104. Tsunoda S, Kawano N, Miyado K, Kimura N, Fujii J.
Impaired fertilizing ability of Sod1-deficient mouse sperm during in-vitro fertilization
Biol Reprod, 87:1-6 (2012)  
103. Takahashi M, Miyata S, Fujii J, Inai Y, Ueyama S, Araki M, Soga T, Fujinawa R, Nishitani C, Ariki S, Shimizu T, Abe T, Ihara Y, Nishikimi M, Kozutsumi Y, Taniguchi N, Kuroki Y.
 In vivo role of aldehyde reductase.
Bichim Biophys Acta - General Subjects, 1820:1787-1796 (2012) 
102. Kurahashi T, Postnikov YV, Zhou M, Bustin M..
The Nucleosome Binding Protein HMGN1 Interacts with PCNA and Facilitates its Binding to Chromatin.
Mol Cell Biol. 32:1844-1854 (2012) 
 101. Ito R, Takahashi M, Ihara H, Tsukamoto H, Fujii J, and Ikeda Y.
Measurement of Peroxiredoxin-4 in Rat Tissues and Implication of Its Serum Levels as a Potential Marker for Hepatic Disease.
Mol Med Report. 6:379-384 (2012) 
100. Peng D, Ma LH, Smith KM, Zhang X, Sato M, La Mar GN:
Role of propionates in substrate binding to heme oxygenase from Neisseria meningitidis: a nuclear magnetic resonance study.
Biochemistry. 51: 7054-63 (2012)  
【2011】 
99. Peng D, Satterlee JD, Ma LH, Dallas JL, Smith KM, Zhang X, Sato M, and La Mar GN.
Influence of substrate modification and C-terminal truncation on the active site structure of substrate-bound heme oxygenase from Neisseriae meningitidis. A 1H NMR study.
Biochemistry. 50:8823-33 (2011) 
98.

Yim SH, Kim YJ, Oh SY, Fujii J, Zhang Y, Gladyshev VN, and Rhee SG.
Identification and characterization of an alternatively transcribed form of peroxiredoxin IV that is specifically expressed in spermatids of the postpubertal mouse testis.
J Biol Chem, 286:39002-39012 (2011) 

 97. Ito J, Saito T, Iwaba A, Suzuki Y, Sanjo M, Ishii R, Sato C, Haga H, Okumoto K, Nishise Y, Watanabe H, Saito K, Togashi H, Kawata K.
A case of monocular blindness as the initial presentation of hepatocellular carcinoma with skull metastasis.
Clin J Gastroenterol
. 4:273-277(2011) 
96.

Palande K, Roovers O, Gits J, Verwijmeren C, Iuchi Y, Fujii J, Neel BG, Karisch R, Tavernier J, and Touw IP.
Peroxiredoxin-controlled G-CSF signalling at the endoplasmic reticulum-early endosome interface.
J Cell Sci 124:3695-3705 (2011)

 95. Ishii R, Togashi H, Iwaba A, Sato C, Haga H, Sanjo M, Okumoto K, Nishise Y, Ito JI, Watanabe H, Saito K, Okada A, Takahashi K, Saito T, Kawata S. (99m)Tc-GSA SPECT analysis was clinically useful to evaluate the effect of interferon in a patient with interferon non-responsive chronic hepatitis C.
Ann Nucl Med. 25:520-523 (2011)
94. Rochman M, Taher L, Kurahashi T, Cherukuri S, Uversky VN, Landsman D, Ovcharenko I, Bustin M.
Effects of HMGN variants on the cellular transcription profile.
Nucleic Acids Res. 39:4076-4087 (2011) 
93. Haga H, Saito T, Okumoto K, Ugajin S, Sato C, Ishii R, Nishise Y, Ito J, Watanabe H, Saito K, Togashi H, Kawata S.
Enhanced expression of fibroblast growth factor 2 in bone marrow cells and its potential role in the differentiation of hepatic epithelial stem-like cells into the hepatocyte lineage.
Cell Tissue Res. 343:371-378 (2011) 
92. Onuma K, Suenaga Y, Sakaki R, Yoshitome S, SatoY , Ogawara S, Suzuki S, Kuramitsu M, Yokoyama H, Murakami A, Hamada J, Nicolson GL, Kobayashi M, Fujii J, and Okada F.
Development of a Quantitative Bioassay to Assess Preventive Compounds against Inflammation-based Carcinogenesis
Nitric Oxide, 25:183-194 (2011)
91. Ikeda Y, Nakano M, Ihara H, Ito R, Taniguchi N, Fujii J.
Different consequences of the reactions with hydrogen peroxide and t-butyl hydroperoxide in the hyperoxidative inactivation of rat peroxiredoxin-4.
J. Biochem. 149:443-453 (2011)
【2010】
 90. Kurahashi T, Furusawa T, Ueda T: Bustin M.
The nucleosome binding protein HMGN3 is expressed in pancreatic alpha-cells and affects plasma glucagon levels in mice.
J Cell Biochem.  109:49-57 (2010) 
89. Hattori E, Shu HJ, Saito T, Okumoto K, Haga H, Yokozawa J, Ito J, Watanabe H, Saito K, Togashi H, Kawata S.
Expression of the RNA-binding protein Musashi1 in adult liver stem-like cells.
Hepatol Res. 40:432-437 (2010)
88. Nishise Y, Saito T, Makino N, Okumoto K, Ito JI, Watanabe H, Saito K, Togashi H, Ikeda C, Kubota I, Daimon M, Kato T, Fukao A, Kawata S.
Relationship between Alcohol Consumption and Serum Adiponectin Levels: The Takahata Study--A Cross-Sectional Study of a Healthy Japanese Population.
J Clin Endocrinol Metab. 95:3828-3835 (2010) 
87. Sanjo M, Saito T, Ishii R, Nishise Y, Haga H, Okumoto K, Ito J, Watanabe H, Saito K, Togashi H, Fukuda K, Imai Y, El-Shamy A, Deng L, Shoji I, Hotta H, Kawata S.
Secondary structure of the amino-terminal region of HCV NS3 and virological response to pegylated interferon plus ribavirin therapy for chronic hepatitis C.
J Med Virol. 82:1364-1370 (2010) 
86. Peng D, Ma LH, Ogura H, Yang EC, Zhang X, Yoshida T, La Mar G.
(1)H NMR Study of the Influence of Mutation on the Interaction of the C-Terminus with the Active Site in Heme Oxygenase from Neisseria meningitidis: Implications for Product Release.
Biochemistry. 49:5832-584 (2010)
85. Otaki N, Chikazawa M, Nagae R, Shimozu Y, Shibata T, Ito S, Takasaki Y, Fujii J, Uchida K.
Identification of a lipid peroxidation product as the source of oxidation-specific epitopes recognized by anti-DNA autoantibodies.
J Biol Chem. 285:33834-33842 (2010)
84. Bertolotti M, Yim SH, Masciarelli S, Kim YJ, Garcia-Manteiga JM, Vene' R, Iuchi Y, Kang MH, Fujii J, Rubartelli A, Rhee SG, Sitia R.
B to plasma cell terminal differentiation entails oxidative stress and profound reshaping of the antioxidant responses.
Antioxid Redox Signal. 13:1133-1144 (2010)
83. Iuchi Y, Roy D, Okada F, Kibe N, Tsunoda S, Suzuki S, Takahashi M, Yokoyama H, Yoshitake J, Kondo S, and Fujii J. Spontaneous skin damage and delayed wound healing in SOD1-deficient mice.
Mol. Cell. Biochem. 341:181-194 (2010)
82. Ikeda Y, Ito R, Ihara H, Okada T, and Fujii J.
Expression of N-terminally truncated forms of rat peroxiredoxin-4 in insect cells.
Protein Expr. Purif. 72:1-7 (2010)
81. Kimura N, Tsunoda S, Iuchi Y, Abe H, Totsukawa K, and Fujii J.
Intrinsic oxidative stress causes either two-cell arrest or cell death depending on developmental stage of the embryos from SOD1-deficient mice.
Mol. Hum. Reprod. 16:441-451 (2010)
80. Iuchi Y, Kibe N, Tsunoda S, Suzuki S, Mikami T, Okada F, Uchida K, and Fujii J.
Implication of oxidative stress as a cause of autoimmune hemolytic anemia in the NZB mice.
Free. Radic. Biol. Med. 48:935-944 (2010)
【2009】
79.

Shibasaki T, Iuchi Y, Okada F, Kuwata K, Yamanobe T, Bannai S, Tomita Y, Sato H, and Fujii J.
Aggravation of ischemia-reperfusion-triggered acute renal failure in xCT-deficient mice.

Arch. Biochem. Biophys. 490:63-69 (2009)

78.

Onuma K, Sato Y, Ogawara S, Shirasawa N, Kobayashi M, Yoshitake J, Yoshimura T, Iigo M, Fujii J, and Okada F.
Nano-scaled Particles of Titanium Dioxide Convert Benign Mouse Fibrosarcoma Cells into Aggressive Tumor Cells.
Am. J. Pathol. 175:2171- 2183 (2009)

77.

IUCHI Y, OKADA F, TAKAMIYA R, KIBE N, TSUNODA S, NAKAJIMA O, TOYODA K, NAGAE R, SUEMATSU M, SOGA T, UCHIDA K, and FUJII J
Rescue of Anemia and Autoimmune Responses in SOD1-Deficient Mice by Transgenic Expression of Human SOD1 in Erythrocytes

Biochem. J. 422:313-320 (2009)

76. IUCHI Y, OKADA F, TSUNODA S, KIBE N, SHIRASAWA N, IKAWA M, OKABE M, IKEDA Y, and FUJII J.
Peroxiredoxin 4 knockout results in elevated spermatogenic cell death via oxidative stress.  

Biochem. J. 419:149-158 (2009)
75.

Harvey CJ, Thimmulappa RK, Singh A, Blake DJ, Ling G, Wakabayashi N, Fujii J, Myers A, and Biswal S.
Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress.

Free. Radic. Biol. Med. 46:443-453 (2009)

【2008】
74.

Cui L, Yoshioka Y, Suyari O, Kohno Y, Zhang X, Adachi Y, Ikehara S, Yoshida T, Yamaguchi M, and Taketani S.
Relevant expression of Drosophila heme oxygenase is necessary for the normal development of insect tissues. 
Biochem Biophys Res Commun. 377:1156-61 (2008)

73. Gohya T, Sato M, Zhang X, Migita CT. 
Variation of the oxidation state of verdoheme in the heme oxygenase reaction.

Biochem. Biophys. Res. Commun
. 376:293-298 (2008)
72. Iuchi Y, Kibe N, Tsunoda S, Okada F, Bannai S, Sato H, and Fujii J.
Deficiency of the cystine-transporter gene, xCT, does not exacerbate the deleterious phenotypic consequences of SOD1 knockout in mice.
Mol. Cell. Biochem. 319:125-132 (2008)
【2007】
71. Natsuizaka M, Ozasa M, Darmanin S, Miyamoto M, Kondo S, Kamada S, Shindoh M, Higashino F, Suhara W, Koide H, Aita K, Nakagawa K, Kondo T, Asaka M, Okada F, and Kobayashi M.
Synergistic up-regulation of Hexokinase-2, glucose transporters and angiogenic factors in pancreatic cancer cells by glucose deprivation and hypoxia.
Exp Cell Res 313: 3337-3348 (2007)
70. Cui H, Darmanin S, Natsuisaka M, Kondo T, Asaka M, Shindoh M, Higashino F, Hamuro J, Okada F, Kobayashi M, Nakagawa K, Koide H, and Kobayashi M.
Enhanced expression of asparagine synthetase under glucose-deprived conditions protects pancreatic cancer cells from apoptosis induced by glucose deprivation and cisplatin.
Cancer Res 67: 3345-3355 (2007)
69. Miseki T, Kawakami H, Natsuizaka M, Darmanin S, Cui HY, Chen J, Fu Q, Okada F, Shindo M, Higashino F, Asaka M, Hamuro J, and Kobayashi M
Suppression of tumor growth by intra-muscular transfer of naked DNA encoding adrenomedullin antagonist.
Cancer Gene Ther 14: 39-44 (2007)
68. Suto D, Iuchi Y, Ikeda Y, Sato K, Ohba Y, and Fujii J.
Inactivation of cysteine and serine proteases by singlet oxygen.
Arch. Biochem. Biophys. 461:151-158, 2007 (IF=3.152, CI= )
67. Iuchi Y, Okada F, Onuma K., Onoda T, Asao H, Kobayashi M, and Fujii J.
Elevated oxidative stress in erythrocytes due to an SOD1 deficiency causes anemia and triggers autoantibody production.
Biochem J,402:219-227, 2007 (IF=4.326, CI= )
66. Yamanobe T, Okada F, Iuchi Y, Onuma K, Tomita Y, and Fujii J.
Deterioration of Ischemia/Reperfusion-induced Acute Renal Failure in SOD1-deficient Mice.
Free Radic Res, 41:200-207, 2007 (IF=2.735, CI= )
【2006】
65. Okada F, Kobayashi M, Tanaka H, Kobayashi T, Tazawa H, Iuchi Y, Onuma K, Hosokawa M, Dinauer MC, and Hunt NH
The role of nicotinamide adenine dinucleotide phosphate oxidase-derived reactive oxygen species in the acquisition of metastatic ability of tumor cells.
Am J Pathol 169: 294-302, 2006.
64. Takeda T, Watanab H, Saito T, Saito K, Takeda H, Togashi H, Fujii J, Takasago Y, and Kawata S.
Impaired portal circulation resulting from L-arginine deficiency in patients with lysinuric protein intolerance.
Gut, 55:1526-1527 (2006)  (IF= 6.601, CI= )
63. Tanaka H, Shirkoohi R., Nakagawa K, Qiao H, Fujita H, Okada F,Hamada J-I., Kuzumaki S, Takimoto M, and Kuzumaki N.
siRNA gelsolin knockdown induces epithelial-mesenchymal transition with a cadherin switch in human mammary epithelial cells.
Int J Cancer, (2006) 118:1680-1691
62. Okada F, Shionoya H, Kobayashi M, Kobayashi T, Tazawa H, Onuma K, Iuchi Y, Matsubara N, Ijichi T, Dugas B, and Hosokawa M.
Inflammation-mediated acquisition of metastatic properties of benign mouse fibrosarcoma cells by administration of an orally available superoxide dismutase.
Br J Cancer, (2006) 94:854-862
61. Suto D, Ikeda Y, Fujii J, and Ohba Y.
Structural analysis of amino acids, oxidized by reactive oxygen species and an antibody against N-Formylkynurenine.
J. Clin. Biochem. Nutr. (2006) 38:107-111 (IF=0.189, CI= )
60. Okada F, Tazawa H, Kobayashi T, Kobayashi M, and Hosokawa M.
Involvement of reactive nitrogen oxides for acquisition of metastatic properties of benign tumors in a model of inflammation-based tumor progression.
Nitric Oxide (2006) 14:122-129 (IF= ,CL= )
【2005】
59. Zhao W, Darmanin S, Fu Q,  Chen J, Cui H, Wang J, Okada F, Hamada J-I., Hattori Y-I., KondoT, Hamuro J, Asaka M and Kobayashi M.
Hypoxia suppresses the production of matrix metalloproteinases and migration of human monocyte-derived dendritic cells
.
Eur J Immunol, (2005) 35:3468-3477
58. Wang X., Inoue S, Gu J, Miyoshi E, Noda K, Li W, Mizuno-Horikawa Y, Nakano M, Asahi M, Takahashi M, Uozumi N, Ihara S, Lee S.H, Ikeda Y, Yamaguchi Y, Aze Y, Tomiyama Y, Fujii J, Suzuki S, Kondo A, Shapiro SD, Lopez-Otin C, Kuwaki T, Okabe M, Honke K, and Taniguchi N.
Dysregulation of TGF-β1 receptor activation leads to abnormal lung developmentand emphysema-like phenotype in core fucose-deficient mice.
Proc. Natl. Acad. Sci. USA (2005) 102:15791-15796 (IF=10.260, CI= )
57. Suto D, Sato K, Ohba Y, Yoshimura T, and Fujii J.
Suppression of the pro-apoptotic function of cytochrome c by singlet oxygen via a heme redox state-independent mechanism.
Biochem. J. (2005) 392:399-406 (IF=4.326, CI= )
56. Tatsuya Ishii, Shingo Matsuki, Yoshihito Iuchi, Futoshi Okada, Shinjiro Toyosaki, Yoshihiko Tomita,Yoshitaka Ikeda, and Junichi Fujii.
Accelerated impairment of spermatogenic cells in sod1-knockout mice under heat stress
Free Radic. Res. 39:697-705 (2005) (IF=2.735, CI= )
55. Kaoru Otsu, Kazuaki Sato, Yoshitaka Ikeda, Hirotaka Imai, Yasuhito Nakagawa, Yoshihiro Ohba, and Junichi Fujii.
An abortive apoptotic pathway induced by singelt oxygen is due to the suprression of caspase activation.
Biochem. J. 389:197-223 (2005) (IF=4.326, CI= )
54. Yuki Nagaoka, Kaoru Otsu, Futoshi Okada, Kazuaki Sato, Yoshihiro Ohba, Naoki Kotani, and Junichi Fujii.
Specific inactivation of cysteine protease-type cathepsin by singlet oxygen generated from naphthalene endoperoxides
Biochem. Biophys. Res. Commun. 331:215-223 (2005) (IF=3.055, CI= )
53. Hayashi E, Kuramitsu Y, Okada F, Fujimoto M, Zhang X, Kobayashi M, Iizuka N, Ueyama Y, Nakamura K.
Proteomic profiling for cancer progression: Differential display analysis for the expression of intracellular proteins between regressive and progressive cancer cell lines.
Proteomics 5:1024-1032 (2005) (IF=5.766, CI=  )
52. Masaki Tanito, Yong-Won Kwon, Norihiko Kondo, Jie Bai, Hiroshi Masutani, Hajime Nakamura, Junichi Fujii, Akihiro Ohira, and Junji Yodoi.
Cytoprotective Effects of Oral Geranylgeranylacetone, an Inducer of Thioredoxin and Heat Shock Protein 72, on Light-Induced Retinal Damage in Mice.
J. Neurosci. 25:2396-2404 (2005)  (IF=8.502, CI= )
51. Guang Cheng, Yoshitaka Ikeda, Yoshihito Iuchi, and Junichi Fujii.
Detection of S-glutathionylated proteins by glutathione S-transferase overlay.
Arch. Biochem. Biophys. 435:42-49 (2005) (IF=2.386, CI= )

【2004】
50. Yuki Nagaoka, Yoshihito Iuchi, Yoshitaka Ikeda, and Junichi Fujii.
Glutathione reductase is expressed at high levels in pancreatic islet cells
Redox Rep. 9:321-324 (2004) (IF=1.045, CI= )
49. Niida S, Kawahara M, Ishizuka Y, Ikeda Y, Kondo T, HIbi T, Suzuki Y, Ikeda K, Taniguchi N.
Gamma-Glutamyltranspeptidase stimulates receptor activator of nuclear factor-kB ligand expression independent of its enzymatic activity and serves as a pathological bone-resorbing factor.
J Biol Chem. 279, 5752-5756 (2004)
48. Zhao S, Kuge Y, Nakada K, Mochizuki T, Takei T, Okada F, Tamaki N.
Effect of steroids on [18F] fluorodeoxyglucose uptake in an experimental tumour model.
Nucl. Med. Commun. 25: 727-730 (2004) (IF=1.23, CI= )
47. Hirai A, Tada M, Furuuchi K, Ishikawa S, Makiyama K, Hamada J, Okada F, Kobayashi I, Fukuda H and Moriuchi T.
Expression of AIE-75 PDZ-domain protein induces G(2)/M cell cycle arrest in human colorectal adenocarcinoma SW480 cells.
Cancer Lett. 211: 209-218 (2004) (IF=2.614, CI= )
46. Kaoru Otsu, Yoshitaka Ikeda, and Junichi Fujii.
The accumulation of Mn-superoxide dismutase under metal-depleted conditions: An implicated role of zinc ion for cellular redox balance
Biochem. J. 377: 241-248 (2004) (IF=4.326, CI= )
45. Yoshihito Iuchi, Tomoko Kaneko, Shingo Matsuki, Tatsuya Ishii, Yoshitaka Ikeda, Koji Uchida, and Junichi Fujii.
Carbonyl stress and detoxification ability in the male genital tract and testis of rats.
Histochem. Cell Biol. 121:123-130 (2004) (IF=2.477, CI= )
44. Kaname Uno, Yoshihito Iuchi, Junichi Fujii, Hideaki Sugata, Katsunori Iijima, Katuaki Kato, Tooru Shimosegawa, and Testuhiko Yoshimura.
In vivo study on cross-talk between inducible nitric oxide synthase and cyclooxygenase in rat gastric mucosa: Effect of COX activity on NO production.
J. Pharmacol. Exp. Ther. 309:995-1002 (2004) (IF=3.555, CI= )
43. Gu J, Zhao Y, Isaji T, Shibukawa Y, Ihara H, Takahashi M, Ikeda Y, Miyoshi E, Honke K, Taniguchi N: Beta1,4-N-Acetylglucosaminyltransferase IIIdown-regulates neurite outgrowth induced by costimulation of epidermal growth factor and integrins through the Res/.ERK signaling pathway in PC12 cells.
Glycobiology 2004;14:177-186

【2003】
42. Sasai K, Ikeda Y, Ihara H, Honke K, Taniguchi N.
Caveolin-1 regulates the functional localization of N-acetylglucosaminyltransferase III within the golgi apparatus.
J Biol Chem 278: 25295-25301 (2003)
41. Yoshihito Iuchi, Tomoko Kaneko, Shingo Matsuki, Isoji Sasagawa, and Junichi Fujii.
Concerted changes in the YB2/RYB-a protein and protamine 2 mRNA in the mouse testis under Heat Stress.
Biol. Reprod. 68: 129-135 (2003) (IF=3.508, CI=1)
40. Rina Takamiya, Motoko Takahashi, Theingi Myint, Yong Seek Park, Nobuko Miyazawa, Takeshi Endo, Noriko Fujiwara, Haruhiko Sakiyama, Yoshiko Misonou, Yasuhide Miyamoto, Junichi Fujii, and Naoyuki Taniguchi.
Glycation proceeds faster in mutated Cu, Zn-superoxide dismutases related to familial amyotrophic lateral sclerosis
FASEB J. 17:938-940 (2003) (IF=8.817, CI= )
39. Tsuneko Fujii, Yoshitaka Ikeda, Hidetoshi Yamashita, and Junichi Fujii
Transient elevation of glutathione peroxidase 1 around the time of eyelid opening in the neonatal rat.
J. Ocul. Pharmacol. Ther. 19:361-370 (2003) (IF=1.085, CI= )
38. Tomoko Kaneko, Yoshihito Iuchi, Motoko Takahashi, and Junichi Fujii.
Colocalization of polyol-metabolizing enzymes and immunological detection of fructated proteins in the female reproductive system of the rat.
Histochem. Cell Biol. 119:309-315 (2003) (IF=2.477, CI=1)
37. Shingo Matsuki, Yoshihito Iuchi,Yoshitaka Ikeda, Isoji Sasagawa, Yoshihiko Tomita, and Junichi Fujii
Suppression of cytochrome c release and apoptosis in testes with heat stress by minocycline.
Biochem. Biophys. Res. Commun. 312: 843-849 (2003) (IF=3.055, CI= )

【2002】
36. Tsuneko Fujii, Takeshi Endo, Junichi Fujii, and Naoyuki Taniguchi.
Differential epression of glutathione reductase and cytosolic glutathione peroxidase, GPX1, in developing rat lungs and kidneys.
Free Radic. Res. 36: 1041-1049 (2002) (IF=2.735, CI=3)
35. Michiharu Miura, Isoji Sasagawa, Yasuhiro Suzuki, Teruhiro Nakada, and Junichi Fujii.
Apoptosis and expression of apoptosis-related genes in mouse testis following heat exposure.
Fertil. Steril. 77: 787-793 (2002) (IF=2.960, CI=9)
34. Shingo Matsuki, Isoji Sasagawa, Yoshihito Iuchi, and Junichi Fujii.
Impaired expression of peroxiredoxin 4 in damaged testes by artificial cryptorchidism
Redox Rep. 7:276-278 (2002) (IF=1.045, CI=1)
33. Tomoko Kaneko, Yoshihito Iuchi,Takashi Kobayashi, Tsuneko Fujii, Hidekazu Saito, Hirohisa Kurachi, and Junichi Fujii.
Expression of glutathione reductase in the male reproductive system of rats supports the enzymatic basis of glutathione function in spermatogenesis.
Eur. J. Biochem. 269: 1570-1578. (2002) (IF=2.849, CI=5)
32. Takashi Kobayashi, Tomoko Kaneko, Yoshihito Iuchi, Shingo Matsuki, Motoko Takahashi, Isoji Sasagawa, Teruhiro Nakada, and Junichi Fujii
Localization and physiological implication of aldose reductase and sorbitol dehydrogenase in male reproductive systems, qccessory glands, and spermatozoa of rats
J. Androl. 23: 674-683 (2002) (IF=2.128, CI=4)
31. Takashi Kobayashi, Teruhiro Nakata, and Takejiro Kuzumaki. 
Effect of flavonids on cell progression in prostate cancer cells.
Cancer Lett. 176; 17-23 (2002)

【2001】
30. Tsuneko Fujii, Junichi Fujii, and Naoyuki Taniguchi.
Augmented expression of peroxiredoxinVI in rat lung and kidney after birth implies an antioxidative role.
Eur. J. Biochem. 268:218-224 (2001) (IF=3.307, CI=15)
29. Vladimir V. Shuvaev, Isabelle Laffont, Jean-Marie Serot, Junichi Fujii, Naoyuki Taniguchi, and Gerard Siest.
Increased protein glycation in cerebrospinal fluid of Alzheimer's disease.
Neurobiol. Aging 22:397-402 (2001) (IF=3.399, CI=13)
28. Noriko Fujiwara, Tsuneko Fujii, Junichi Fujii, and Naoyuki Taniguchi.
Roles of N-terminal active cysteines and C-terminal cysteine-selenocysteine in the catalytic mechanism of mammalian thioredoxin reductase.
J. Biochem. 129: 803-812 (2001) (IF=2.191, CI=5)
27. Isoji Sasagawa, Shingo Matsuki, Yasuhiro Suzuki, Yoshihito Iuchi, Kazuo Tohya, Michio Kimura, Teruhiro Nakada, and Junichi Fujii
Possible involvement of the membrane-bound form of peroxiredoxin 4 in acrosome formation during spermiogenesis of rats
Eur. J. Biochem. 268: 3053-3061 (2001) (IF=3.307, CI=7)
26. Yoshihito Iuchi, Takashi Kobayashi ,Tomoko Kaneko, Masatoshi Takahara, Toshihiko Ogino, and Junichi Fujii.
The expression of a Y-box protein, YB2/RYB-a, precedes protamine 2 during spermatogenesis in rodents.
Mol. Human Reprod. 7: 1023-1031 (2001) (IF=3.643, CI=5)
25. Tomoko Kanek, Yoshihito Iuchi, Satoshi Kawachiya, Tsuneko Fujii, Hidekazu Saito, Hirohisa Kurachi, and Junichi Fujii.
Alteration of glutathione reductase expression in the female reproductive organs during the estrous cycle.
Biol. Reprod. 65: 1410-1416 (2001) (IF=3.417, CI=8)
24. Tsuneko Fujii, Keiji Mori, Yoshinori Takahashi, Naoyuki Taniguchi, Akira Tonosaki, Hidetoshi Yamashita, and Junichi Fujii.
Multilocal expression and developmental changes in the levels of glutathione reductase in ocular tissues of rats.
Histochem. J. 33: 267-272 (2001) (IF=1.161, CI=3)
23. Rudy J. Castellani, Peggy L. Harris, Lawrence M. Sayre, Junichi Fujii, Naoyuki Taniguchi, Michael P. Vitek, Hank Founds, Craig S. Atwood, George Perry, and Mark A. Smith.
Active glycation in neurofibrillary pathology of Alzheimer disease: Ne-(carboxymethyl) lysine and hexitol-lysine.
Free Radic. Biol. Med. 31: 175-180 (2001) (IF=4.079, CI=13)
22. Kaoru Otsu, Kikukatsu Ito, Takejiro Kuzumaki, Yoshihito Iuchi.
Differential regulation of liver-specific and ubiquitously-expressed genes in primary rat hepatocytes by the extracellular matrix.
Cell.Physiol. Biochem. 11: 33-40 (2001) (IF=1.276).
21. Paul F. Gomez, Dong Luo, Kuninori Hirosaki, Kyoka Shinoda, Toshihsru Yamashita, Jun-ichi Suzuki, Kaoru Otsu, Kiichi Ishikawa, and Kowichi Jimbow.
Identification of rab7 as a melanosome-associated protein involved in the intracellular transport of tyrosinase-related protein 1.
J. Invest. Dermatol. 117, 81-90 (2001)

【2000】
20. Seiji Kikuchi, Akihiko Ogata, Kazuyoshi Shinpo, Fumio Moriwaka, Junichi Fujii, Naoyuki Taniguchi, and Kunio Tashiro
Detection of an Amadori product, 1-hexitol-lysine, in the anterior horn of the amyotrophic lateral sclerosis and spinobulbar muscular atrophy spinal cord: Evidence for early involvement of glycation in motoneuron diseases.
Acta Neuropathol. 99: 63-66 (2000) (IF=2.402, CI=4)
19. Hideaki Miwa, Junichi Fujii, Hiroyuki Kanno, Naoyuki Taniguchi, and Katsuyuki Aozasa
Pyruvate secreted by human lymphoid cell lines protects cells from hydrogen peroxide mediated apoptosis.
Free Radic. Res. 33: 45-56 (2000) (IF=2.270, CI=8)
18. Ayako Okado-Matsumoto, Theingi Myint, Junichi Fujii, and Naoyuki Taniguchi.
Gain in functions of mutant Cu,Zn-superoxide dismutases as a causative factor in familial amyotrophic lateral sclerosis: Less reactive oxidant formation but high spontaneous aggregation and precipitation.
Free Radic. Res. 33: 65-73 (2000) (IF=2.270, CI=13)
17. Ayako Okado-Matsumoto, Akio Matsumoto, Junichi Fujii, and Naoyuki Taniguchi.
Peroxiredoxin IV is a secretable protein with heparin-binding properties under reduced conditions.
J. Biochem.127: 493-501 (2000) (IF=2.191, CI=28)
16. Yukihiro Yamaguchi, Yoshitaka Ikeda, Tomoaki Takahashi, Hideyuki Ihara, Tatsuya Tanaka, Junichi Fujii, and Naoyuki Taniguchi.
Genomic structure and promoter analysis of the human a1,6fucosyltransferase gene (FUT8)
Glycobiology 10: 637-643 (2000) (IF=3.728, CI=7)
15. Tsuneko Fujii, Rieko Hamaoka, Junichi Fujii, and Naoyuki Taniguchi.
Redox capacity of cells affects inactivation of glutathione reductase by nitrosative stress.
Arch. Biochem. Biophys. 378: 123-130 (2000) (IF=2.386, CI=9)
14. Takeshi Endo, Tsuneko Fujii, Kenzo Sato, Naoyuki Taniguchi, and Junichi Fujii.
A pivotal role of Zn-binding residues in the function of the copper chaperone for SOD1.
Biochem. Biphys. Res. Commun. 276: 999-1004 (2000) (IF=3.161, CI=1)
13. Ayako Okado-Matsumoto, Akio Matsumoto, Junichi Fujii, and Naoyuki Taniguchi. Effect of cAMP on inducible nitric oxide synthase gene expression; Its dual and cell specific functions.
Antioxid. Redox Signal. 2: 631-642 (2000) (IF=3.037, CI=1)
12. Yumiko Takano, Yoshihito Iuchi, Jun-itsu Ito, Kaoru Otsu, Takejiro Kuzumaki, Kiichi Ishikawa
Characterization of the responsive elements to hormones in the rat aldolase B gene.
Arch. Biochem. Biophys. 377: 58-64. (2000) (IF=2.386)
11. Xia Wang, Kaoru Otsu, Hidekazu Saito, Masahiko Hiroi, and Kiichi Ishikawa.
Sandwich configuration of type I collagen suppresses progesterone production in primary cultured porcine granulosa cells by reducing gene expression of cytochrome P450 cholesterol side-chain cleavage enzyme.
Arch. Biochem. Biophys. 376, 117-123 (2000) (IF=2.386)

【1999】
10. Urayama M,Ishiyama S,Kuzumaki T,Ishikawa K,Fuse A,Kuzu H,Igarashi Y,Suto K,Tsukamoto M
Change of liver function in hypertrophying lobe of rabbit liver after portal branch ligation.
J Surg Res 1999;86:55-61
9. Ohta N,Saito H,Kuzumaki T,Takahashi T,Ito M M,Saito T, Nakahara K,Hiroi M
Expression of CD44 in human cumulus and mural granulosa cells of individual patients in in-vitro fertilization programmes.
Mol Human Reproduction 1999;5:22-28
8. Akio Matsumoto, Ayako Okado, Tsuneko Fujii, Junichi Fujii, Masayuki Egashira, Norio Niikawa, and Naoyuki Taniguchi.
Cloning of Peroxiredoxin Gene Family in Rats and Characterization of the Fouth Member.
FEBS Lett. 443:246-250 (1999) (IF=3.720, CI=38)
7. Yukihiro Yamaguchi, Junichi Fujii, Shinya Inoue, Naofumi Uozumi, Shusaku Yanagidani, Yoshitaka Ikeda, Masayuki Egashira, Osamu Miyoshi, Norio Niikawa, and Naoyuki Taniguchi.
Mapping of the a1,6Fucosyltransferase Gene, FUT8, to Human Chromosome 14q24.3.
Cytogenet. Cell Genet. 84: 58-60 (1999) (IF=1.604, CI=6)
6. Junichi Fujii, Rieko Hamaoka, Akio Matsumoto, Tsuneko Fujii, Yukihiro Yamaguchi, Masayuki Egashira, Osamu Miyoshi, Norio Niikawa, and Naoyuki Taniguchi.
The Structural Organization of the Human Aldehyde Reductase Gene, AKR1A1, and Mapping to Chromosome 1p32-p33.
Cytogenet. Cell Genet. 84: 230-232 (1999) (IF=1.604, CI=1)
5. Makoto Hasegawa, Yuki Kawano, Yoshiko Matsumoto, Yuji Hidaka, Junichi Fujii, Naouyuki Taniguchi, Akihiro Wada, Toshiya Hirayama, and Yasutsugu Shimonishi.
Expression and Characterization of the Extracellular Domain of Guanylyl Cyclase C from a Baculovirus and Sf21 Insect Cells.
Protein Expr. Purif. 15: 271-281 (1999) (IF=1.416, CI=6)
4. Rieko Hamaoka, Yuji Yaginuma, Tomoaki Takahashi, Junichi Fujii, Masahiko Koizumi, Han Geuk Seo, Yutaka Hatanaka, Kaoru Hashizume, Kunio Ii, Toshiaki Hanafusa, Yuji Matsuzawa, Mutsuo Ishikawa, and Naoyuki Taniguchi
Different Expression Patterns of Nitric Oxide Synthase Isozymes in Various Gynecological Cancers
J. Cancer Res. Clin. Oncol. 125: 321-326 (1999) (IF=1.052, CI=3)
3. Noriko Fujiwara, Tsuneko Fujii, Junichi Fujii, and Naoyuki Taniguchi.
Functional Expression of Rat Thioredoxin Reductase: Selenocysteine Insertion Sequence Element Is Essential for the Active Enzyme.
Biochem. J. 340: 439-444 (1999) (IF=4.349, CI=24)
2. Rieko Hamaoka, Junichi Fujii, Jun-ichiro Miyagawa, Motoko Takahashi, Michihiko Kishimoto, Makoto Moriwaki, Koji Yamamoto, Yoshitaka Kajimoto, Yoshimitsu Yamasaki, Toshiaki Hanafusa, Yuji Matsuzawa, and Naoyuki Taniguchi.
Overexpression of the Aldose Reductase Gene Induces Apoptosis in Pancreatic b-Cells by Causing Redox Imbalance.
J. Biochem. 126: 41-47 (1999) (IF=2.191, CI=10)
1. Vladimir V. Shuvaev, Junichi Fujii, Yoshimi Kawasaki, Hidehiko Itoh, Rieko Hamaoka, Anne Barbier, Olivier Ziegler, Gerard Siest, and Naoyuki Taniguchi
Glycation of Apolipoprotein E Impairs Its Binding to Heparin. Identification of the Major Glycation Site
Biochim. Biophys. Acta 1454: 296-308 (1999) (IF=2.590, CI=12)

 Books, Reviews, and Proceedings

【2016】
41. Junichi Fujii, Takujiro Homma, Sho Kobayashi.
Chapter 11; Ascorbic Acid as a Multifunctional Nutrient in Mammals; Our Understanding based on Studies using Genetically Modified Mice.
In"
Ascorbic Acid: Properties, Synthesis and Applications"(Emma Parsons, ed)
Nova Science Publishers, Inc, 239-265 (2016)
   
40. Takujiro Homma, Junichi Fujii.
Chapter 2; Indispensable Roles of Superoxide Dismutation in Mammalian Erythrocytes.
In "
Superoxide Dismutase (SOD): Sources, Therapeutic Uses and Health Benefits." (Nancy H. Phillips, ed.)
Nova Science Publishers, Inc, 37-57 (2016)
   
【2015】  
 39. Takujiro Homma, Junichi Fujii.
Application of glutathione as anti-oxidative and anti-aging drug.
Curr Drug Metab, 16:560-571 (2015) (invited review)  
 38.

Toshihiro Kurahashi, Junichi Fujii.
Roles of Antioxidative Enzymes in Wound Healing.
J Dev Biol, 3(2):57-70 (2015) (invited review)  

 37. Junichi Fujii, Toshihiro Kurahashi, Tasuku Konno, Takujiro Homma, Yoshihito Iuchi.
Oxidative stress as a potential causal factor for autoimmune hemolytic anemia and systemic lupus erythematosus
World J Nephrol, 4(2):213-222 (2015) (invited review) 
36. Junichi Fujii, Yoshitaka Ikeda, Toshihiro Kurahashi, Takujiro Homma.  
Physiological and Pathological Views of Prdx4.
Free Radic. Biol. Med, 83:373-379 (2015) (invited review)   
【2014】  
 35. Junichi Fujii, and Hirotaka Imai.
Redox reactions in mammalian spermatogenesis and the potential targets of reactive oxygen species under oxidative stress.
Spermatogenesis, 4(2):e979108 (2014) (invited review)   
34. Junichi Fujii
Chapter 6. Catalytic Protein-Enzymes
in "Medical Biochemistry 4th ed" (J. W. Baynes and M. H. Dominiczak eds.)
Elsevier, London, 54-67 (2014)
  
33. Tsunoda S, Kimura N, and Fujii J.
Oxidative stress and redox regulation of gametogenesis, fertilization, and embryonic development. 
Reproductive Medicine and Biology, 13:71-79 (2014)   
32. Fujii J, Tsunoda S, and Kimura N.
Antithetical Roles of Reactive Oxygen Species in Mammalian Reproduction.
in "Handbook of System Biology of Free Radicals and Anti-oxidants"  (I. Larher ed),
Springer-Verlag, Germany, 2705-2721 (2014)
  
【2011】 
31. Fujii J, and Tsunoda S
Redox regulation of spermatogenic process and fertilization
Asian J Androl, 13:420-423 (2011)
30. Fujii J, Ito JI, Zhang X, and Kurahashi T.
Unveiling the Roles of the Glutathione Redox System In Vivo by Analyzing Genetically Modified Mice
.
J. Clin. Biochem. Nutr. 49:70-78, (2011)
29. Fujii J,
Introduction to serial reviews: physiological relevance of antioxid/redox genes; learning from genetically modified animals.

J. Clin. Biochem. Nutr. 49:69, (2011)
【2010】 
28.

Fujii J and Iuchi Y.
Requirement of Multiple Antioxidative/Redox Systems to Support Male Fertility.
In "Male and Female Infertility: Genetic Causes, Hormonal Treatments and Health Effects." (Bjorn Glantz and Klas Edquist eds), Nova Science Publishers, Inc, p33-54 (2010)

27.

Kimura N and Fujii J.
Active oxygen species as a signal of embryonic developmental arrest and death,
In "Male and Female Infertility: Genetic Causes, Hormonal Treatments and Health Effects." (Glantz B and Edquist K eds), Nova Science Publishers, Inc, p55-75 (2010)

【2009】
26. Junichi Fujii
Chapter 6. Catalytic Protein-Enzymes
in "Medical Biochemistry 3rd ed" (M. H. Dominiczak and J. W. Baynes eds.)
Mosby/Elsevier, London, 59-71 (2009)
【2008】
25. Okada F and Kobayashi H.
How aging and cellular senescence influence metastasis.
In: Cancer metastasis: biologic basis and therapeutic (Eds. D.R. Welch and D.C. Lyden) Cambridge University Press. New York, 2008, in press
【2007】
24. Okada F.
Beyond foreign-body-induced carcinogenesis: Impact of reactive oxygen species derived from inflammatory cells in tumorigenic conversion and tumor progression.
Int J Cancer 121: 2364-2372, 2007.
23. Y. Iuchi, F. Okada, K. Onuma, M. Kobayashi, J. Fujii.
Oxidative stress in erythrocytes; A cause for anemia and autoimmune response.
3rd International Meeting of the Society for Free Radical Research-Asia. Medimond, Bologna,71-73 (2007)
【2006】
22. Futoshi Okada and Junichi Fujii.
Molecular mechanisms of inflammation-induced carcinogenesis.
J Clin Biochem Nutr, 39:103-113 (2006)
【2005】
21. Junichi Fujii, Yoshihito Iuchi,and Futoshi Okada.
Fundamental roles of reactive oxygen species and protective mechanisms in the female reproductive system.
Reprod Biol Endocrinol, 3:43 (10 pages) (2005) review  (IF=2.74, CI= )
20. G. Cheng, Y. Ikeda, Y. Iuchi, and J. Fujii.
A novel method to detect S-glutathionylated proteins by glutathione S-transferase.
in "Natural Antioxidants and Micronutrients" (B Zhao, G Liu, L Packer, eds), Medimond, Bologna, 155-158 (2005)
19. D. Suto, K. Sato, Y. Ohba, T. Yoshimura, and J. Fujii.
Abolished pro-apoptotic function of cytochrome c by singlet oxygen via heme redox state-independent mechanism.
in "Natural Antioxidants and Micronutrients "(B Zhao, G Liu, L Packer, eds), Medimond, Bologna, 87-90 (2005)
18. Futoshi Okada and Junichi Fujii.
Prevention of tumor progression as the ultimate goal of cancer therapy.
Cancer Therapy 3: 219-226 (2005)
17. Junichi Fujii
Chapter 5. Catalytic Protein-Enzymes
in "Medical Biochemistry 2nd ed" (M. H. Dominiczak and J. W. Baynes eds.)
Mosby, London, 51-62 (2005)
【2004】
16. J. Fujii, K. Otsu, Y. Ikeda, S. Sato, Y. Ohba.
Elucidation of Singlet Oxygen-Induced Cell Death.
In "Proceeding of XII Biennial Meeting of SFRR", Monduzzi Editore, 305-309 (2004)
2003】
15. Junichi Fujii, Yoshihito Iuchi, Shingo Matsuki, Tatsuya Ishii.
Cooperative function of antioxidant and redox systems against oxidative stress in male reproductive tissues
Asian J. Androl. 5:231-242 (2003) (IF=1.064, CI=3)
【2002】
14. J. Fujii, T. Kaneko, Y. Iuchi.
Glutathione Redox Status in the Rat Reproductive System.
In “XI Biennial Meeting of the Society for Free Radical Research International” (C.Pasquier ed), Bologna, Monduzzi Editore, C716: 217-220 (2002)
13. Junichi Fujii, Yoshitaka Ikeda.
Advances in our understanding of peroxiredoxin, a multifunctional, mammalian redox protein.
Redox Rep. 7: 123-130 (2002) (IF=0.717, CI=56)
12. Junichi Fujii, Tomoko Kaneko, Takashi Kobayashi,Yoshihito Iuchi, Motoko Takahashi.
Localization and Physioloigcal Implication of Polyol-Metabolyzing Enzymes in Male and Female Reproductive Systems of Rat
In "The Maillard Reaction in Food Chemistry and Medical Science: Update for the Postgenomic Era" (S. Horiuchi, T. Kurata, N. Taniguchi, T. Osawa, F. Hayase, Eds), Amsterdam, Elsevier, 363-364 (2002)
【2001】
11. S. Kikuchi, K. Shinpo, J. Fujii, Z. Makita, M. Takeuchi, N. Taniguchi, and K. Tashiro.
Abnormal Glycation in ALS.
in "Molecular Mechanism and Therapeutics of Amyotrophic Lateral Sclerosis" (K. Abe, Ed), Elsevier, 255-263 (2001)
【2000】
10. J. Fujii.
6. Detection of nitric oxide synthase (NOS) expression: preparation of RNA.
in "Experimental Protocols for Reactive Oxygen and Nitrogen Species" (N. Taniguchi and J.M.C. Gutteridge Eds), Oxford Press, 194-196 (2000)
9. J. Fujii.
28. Nitric oxide synthase (NOS) activity assay: determination of produced NADP+.
in "Experimental Protocols for Reactive Oxygen and Nitrogen Species" (N. Taniguchi and J.M.C. Gutteridge Eds), Oxford Press, 103-105 (2000)
8. J. Fujii.
27. Nitric oxide synthase (NOS) activity assay: RI method to detect L-citrulline.
in "Experimental Protocols for Reactive Oxygen and Nitrogen Species" (N. Taniguchi and J.M.C. Gutteridge Eds), Oxford Press, 101-102 (2000)
7. J. Fujii.
6. NO-generating system.
in "Experimental Protocols for Reactive Oxygen and Nitrogen Species" (N. Taniguchi and J.M.C. Gutteridge Eds), Oxford Press, 25-27 (2000)
6. K. Suzuki, H. Ohno, S. Oh-ishi, T. Kizaki, T. Ookawara, J. Fujii, Z. Radak, and N. Taniguchi.
Superoxide Dismutases in Exercise and Disease.
in "Handbook of Oxidants and Antioxidants in Exercise" (C.K. Sen, L. Packer, and O. Hanninen eds.), Elsevier Science, Amsterdam, 243-295 (2000)
5. Takejiro Kuzumaki.
Regulation of gene expression by changes in cell adhesion.
in “ Progress in Molecular and Subcellular Biology” (Macieira-Coelho A ed.), Springer-Verlag, Heidelberg, 25: 71-87 (2000)
【1999】
4. Junichi Fujii, and Naoyuki Taniguchi
Down Regulation of Superoxide Dismutases and Glutathione Peroxidase by Reactive Oxygen and Nitrogen Species
Free Radic. Res. 31: 301-308 (1999) (IF=2.270, CI=19)
3. Junichi Fujii, Motoko Takahashi, Rieko Hamaoka, Yoshimi Kawasaki, Nobuko Miyazawa, and Naoyuki Taniguchi
Physiological Relevance of Aldehyde Reductase and Aldose Reductase Gene Expression.
Adv. Exp. Med. Biol. (Weiner, H., Maser, E., Crabb, D.W., and Lindahl, R. eds), Academic/Plenum Publishers, New York, 463: 419-426 (1999) (IF=0.446, CI=3)
2. Junichi Fujii
Chapter 5. Catalytic Protein-Enzymes
in "Medical Biochemistry" (M. H. Dominiczak and J. W. Baynes eds.)
Mosby, London, 43-54 (1999)
1. Junichi Fujii and Naoyuki Taniguchi.
Dysfunction of Redox System by Reactive Oxygen and Nitrogen Species.
in "Redox Regulation of Cell Signaling and Its Clinical Applications"
(J. Yodoi and L. Packer eds), Marcel Dekker, Basel, 11-24 (1999)

 【和文:著書、総説、論文、他】

 
【2017】
49. 金野祐藤井順逸
血球細胞の酸化障害と血液関連自己免疫疾患 「生化学, みにれびゅう」89;81-85 (2017)、 日本生化学会、東京
  
【2016】  
48. 藤井順逸, 本間拓二郎, 小林翔.
グルタチオン:古いレドックス分子の新たな役割.
TH LUNG perspectives、メディカルレビュー社、 24(4);421-425(2016) 
  
【2014】  
47. 藤井順逸 
自己免疫疾患と酸化ストレス 
「酸化ストレスの医学(第2版)」 吉川敏一監修 内藤裕二・豊國伸哉 編  427-433 (2014) 診断と治療社
 
46. 藤井順逸
14-4 活性酸素 213-215 (2014)
シンプル生化学(改訂6版) 、林典夫・廣野浩子監修、野口正人・五十嵐和彦編集、南江堂、東京
【2012】  
45.  藤井順逸, 倉橋敏裕, 伊藤純一, 張旭紅
細胞内外で多様な機能を発揮するレドックス分子・ぺルオキシレドキシン-4.
日本応用酵素協会誌.  46: 1-9 (2012) 
44.  藤井順逸: 
酸化ストレスと女性生殖機能-活性酸素のもつ細胞内シグナルとしての役割-
Hormone Frontier in Gynecology 19:143-147 (2012) 
43. 

藤井順逸: 
細胞増殖に関わるリン酸化・脱リン酸化の制御における活性酸素種のシグナル伝達分子としての役割.
Vitamemebrane 12:1-9 (2012)

【2010】  
42.  伊藤純一, 河田純男:
NASH/NAFLDの診断・治療 臨床経過I:通常型. 大畑秀穂偏, 「臨床栄養臨時増刊 NASH/NAFLDのすべて」 東京; 医歯薬出版, 2010:689-693
41. 伊藤純一, 河田純男:
原発性硬化性胆管炎におけるゲノムワイド関連解析.
Review of Gastroenterology & Clinical Gastroenterology and Hepatology 5:59-63 (2010)
40.  伊藤純一, 鈴木明彦, 宇賀神智, 佐藤智佳子, 芳賀弘明, 石井里佳, 三條麻衣, 奥本和夫, 西瀬雄子, 渡辺久剛, 斎藤孝治, 斎藤貴史, 河田純男:
高齢者に発症した肝動注化学塞栓療法(TACE)後のガス産生肝膿瘍の1例.
日本高齢者消化器病学会誌. 12(2):83-87 (2010)
39.  松尾拓, 王玉来, 五十嵐貴宏, 齋藤吉彦, 鈴木恒治, 平田慎也, 伊藤純一, 山川徳光:
シスプラチン/リピオドール懸濁液による肝動脈化学療法後に急速に浸潤性増殖をきたし、診断に苦慮した肝細胞癌の1例. 肝肝臓. 51:447-452 (2010)
38. 藤井順逸
ペントースリン酸経路
「ことばのカルテ-メディカルトリビューン-」2月号 (2010) メディカルトリビューン社
【2009】 
37. 藤井順逸
ペルオキシレドキシン
「ことばのカルテ-メディカルトリビューン-」11月19日号 (2009) メディカルトリビューン社
36.

岡田太小沼邦重藤井順逸
運動とがんと免疫、293-299 (2009)

「運動と免疫-からだをまもる運動のふしぎ」 大野秀樹、木崎節子 編著、NAP Limited、東京

35.

岡田太小沼邦重藤井順逸 
運動と大腸がんと免疫、300-303 (2009)

「運動と免疫-からだをまもる運動のふしぎ」 大野秀樹、木崎節子 編著、NAP Limited、東京

34.

岡田太小沼邦重藤井順逸 
運動と乳がんと免疫、304-306 (2009)

「運動と免疫-からだをまもる運動のふしぎ」 大野秀樹、木崎節子 編著、NAP Limited、東京

33.

井内良仁藤井順逸
運動と生殖系と免疫、121-123 (2009)
「運動と免疫-からだをまもる運動のふしぎ」 大野秀樹、木崎節子 編著、NAP Limited、東京

32. 藤井雅典,大和田一雄,藤井順逸,
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)誘発一側性サルパーキンソン病モデルの確立.
山形医学 27:119-133 (2009)
31. 藤井順逸
酸化ストレスによる貧血-造血幹細胞の老化と赤血球の酸化
「実験医学増刊:活性酸素シグナルと酸化ストレス」谷口直之監修 赤池孝章・鈴木敬一郎・内田浩二 編
164-168 (2009) 羊土社、東京
30. 岡田 太
発癌・悪性化における癌間質としての炎症細胞の役割

「実験医学増刊: 病態の理解と治療をめざす癌と微小環境」 江角浩安、高倉伸幸、宮園浩平、森  正樹 編
85-90 (2009) 羊土社、東京
29. 藤井順逸
Sーアデノシルメチオニン脱炭酸酵素
ガンマ-ジーティーピー
ガンマ-ジーティーピーアイソザイム
グルタチオンSートランスフェラーゼ
グルタチオン還元酵素
グルタチオンシンテターゼ
グルタチオンペルオキシダーゼ
トランスヒドロゲネーション
転移酵素
リボザイム
「医学書院医学大辞典・改定版」印刷中(2008)、医学書院
【2008】
28. 岡田 太
異物発癌・転移モデル
「がん転移研究の実験手法」(日本がん転移学会編/済木育夫・愛甲 孝 編集責任,金芳堂) pp.117-125(2008)
27. 藤井順逸 
自己免疫疾患と酸化ストレス 
「酸化ストレスの医学」 吉川敏一監修 内藤裕二・豊國伸哉 編  371-377 (2008) 診断と治療社
【2007】
26. 藤井順逸
リアノジン受容体
「ことばのカルテ-メディカルトリビューン-」 6月7日号 (2007) メディカルトリビューン社
【2006】
25. Ian F. Tannok, Richard P. Hill eds (4th edition) 谷口直之、大島明、鈴木敬一郎監訳
The Basic Scinece of Oncology 「がんのベーッシックサイエンス(日本語第3版)」(2006) 
メディカルイサイエンスインターナショナル、東京
24. 岡田 太
炎症発癌と活性酸化窒素種

「別冊医学のあゆみ:酸化ストレス-フリーラジカル医学生物学の最前線ver2」 143-146(2006) 医歯薬出版、東京
23.

藤井順逸
男性生殖における酸化反応の功罪

「別冊医学のあゆみ:酸化ストレス-フリーラジカル医学生物学の最前線ver2」
435-438(2006)医歯薬出版、東京

22. 藤井順逸
運動と老化の生化学
「標準理学療法学・基礎理学療法学」(内山靖 編)
35-45 (2006)医学書院、東京
【2005】
21. 岡田 太
炎症による発癌・プログレッションモデルと化学予防.
「日本がん予防学会News Letter」 45, 8-9, (2005) 医歯薬出版、 東京
20. 藤井順逸
書評
 (仁木鋭雄 他編「酸化ストレスマーカー」, 学会出版センター)
「生化学」 1225-1226 (2005)
日本生化学会
【2004】
19. 藤井順逸
核酸の研究法
医学を学ぶための生物学 改訂第2版」(谷口直之、米田悦啓、編著)
472-478 (2004)南江堂、東京
18. 岡田 太
一酸化窒素による癌細胞のプログレッション
「別冊 医学のあゆみ」132-137(2004)医歯薬出版、 東京
17. 藤井順逸
レドックス制御
「ことばのカルテ-メディカルトリビューン-」8月21日号 (2004)メディカルトリビューン社
16. 池田義孝
翻訳後修飾
「ことばのカルテ-メディカルトリビューン」メディカルトリビューンVol.37, No. 14 (2004)
15. 藤井順逸、谷口直之
一酸化窒素
「Key Word 糖尿病 第2版」(河盛隆造、春日雅人、田嶼尚子、編)先端医療社32-33 (2004)
【2003】
14. 藤井順逸
Sーアデノシルメチオニン脱炭酸酵素
ガンマ-ジーティーピー
ガンマ-ジーティーピーアイソザイム
グルタチオンSートランスフェラーゼ
グルタチオン還元酵素
グルタチオンシンテターゼ
グルタチオンペルオキシダーゼ
トランスヒドロゲネーション
転移酵素
リボザイム
「医学書院医学大辞典」(2003)、医学書院
【2001】
13. 藤井順逸
4-2 ミトコンドリアの抗酸化酵素
「新ミトコンドリア学」218-224 (2001)、共立出版
12. 藤井順逸
45. SOD1 変異による筋萎縮性側索硬化症の発症とCuシャペロンの役割
「酸化ストレスの基礎と臨床」182-185(2001)、医歯薬出版
11. 藤井順逸
PCR法:その原理と応用
「医学研究のためのテクニカルガイダンス」(谷口直之編)18-25(2001)、メディカルレビュー社
10. 藤井順逸
Q98 血液再准潅流はなぜ危険なのか?
「運動と遺伝 Q & A」202-203 (2001)、大修館書店
9. 藤井順逸
Q93 抗酸化ビタミンは効果があるのか?
「運動と遺伝 Q & A」192-193 (2001)、大修館書店
8. 藤井順逸
Q44 膵島ホルモンの反応は?
「運動と遺伝 Q & A」90-91 (2001)、大修館書店
7. 藤井順逸
Q20 ミトコンドリアの機能は?
「運動と遺伝 Q & A」40-41 (2001)、大修館書店
6. 藤井順逸
酸化ストレスからの防御機構:抗酸化酵素系とレドックス制御系の役割
「山形医学」19: 65-74 (2001)
【2000】
5. 藤井順逸
神経疾患と酸化ストレス
「第5巻 酸化ストレス・レドックスの生化学-バイオサイエンスの新世紀」
(谷口直之、淀井淳司編)154-161 (2000)、共立出版
4. 藤井順逸、谷口直之
老化におけるアポトーシスの意義
「アポトーシスと疾患-中枢神経系疾患編-」(水野美邦編)
102-114 (2000)医薬ジャーナル社、大阪
3. 藤井順逸
活性酸素によるアポトーシスとレドックス制御系の役割
20:39-44 (2000)炎症
【1999】
2. 藤井順逸、谷口直之
神経の老化におけるスーパーオキシドならびにNOの役割」
(谷口直之 編)
「神経研究の進歩」
43: 236-246 (1999)医学書院
1. 藤井恒子、藤井順逸、谷口直之
3. NO の生理活性 (2)発癌との関連
「臨床消化器内科」14: 681-688 (1999)日本医学館、東京

山形大学大学院 医学系研究科 生命環境医科学専攻 生化学・分子生物学講座
〒990-9585 山形市飯田西2-2-2 Tel:023-628-5229 Fax:023-628-5230