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Eun Sil KANG

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Original Papers

  1. Jaeyong Lee, Eun Sil Kang, Sho Kobayashi, Takujiro Homma, Hideyo Sato, Han Geuk Seo, Junichi Fujii
    The viability of primary hepatocytes is maintained under a low cysteine-glutathione redox state with a marked elevation in ophthalmic acid production.
    Exp Cell Res, 361:178-191 (2017)  
  2. Eun Sil Kang, Jaeyong Lee, Takujiro Homma, Toshihiro Kurahashi, Sho Kobayashi, Atsunori Nabeshima, Sohsuke Yamada, Han Geuk Seo, Satoshi Miyata, Hideyo Sato, Junichi Fujii
    xCT deficiency aggravates acetaminophen-induced hepatotoxicity under inhibition of the transsulfuration pathway

    Free Radic Res, 51, 80-90 (2017)  DOI: 10.1080/10715762.2017.1282157 
  3. Toshihiro Kurahashi, Jaeyong Lee, Atsunori Nabeshima, Takujiro Homma, Eun Sil Kang, Yuka Saito, Sohsuke Yamada, Toshiyuki Nakayama, Ken-ichi Yamada, Satoshi Miyata, Junichi Fujii.
    Ascorbic acid prevents acetaminophen-induced hepatotoxicity in mice by ameliorating glutathione recovery and autophagy.
    Arch Biochem Biophys, 604:36-46 (2016)
  4. Toshihiro Kurahashi, Shinji Hamashima, Takaya Shirato, Jaeyong Lee, Takujiro Homma, Eun Sil Kang, Junichi Fujii.
    An SOD1 deficiency enhances lipid droplet accumulation in the fasted mouse liver by aborting lipophagy

    Biochem Biophys Res Commun, 467:866-871 (2015)
  5. Takujiro Homma, Toshihiro Kurahashi, Jaeyong Lee, Eun Sil Kang and Junichi Fujii
    SOD1 deficiency decreases proteasomal function, leading to the accumulation of ubiquitinated proteins in erythrocytes.
    Arch Biochem Biophys, 583:65-72 (2015)  
  6. Jaeyong Lee, Takujiro Homma, Toshihiro Kurahashi, Eun Sil Kang, andJunichi Fujii.
    Oxidative stress triggers lipid droplet accumulation in primary cultured hepatocytes by activating fatty acid synthesis.

    Biochem Biophys Res Commun
    , 464:229-235 (2015) 
  7. Takujiro Homma, Satoshi Okano, Jaeyong Lee, Junitsu Ito, Noriyuki Otsuki, Toshihiro Kurahashi, Eun Sil Kang, Osamu Nakajima, and Junichi Fujii.
    SOD1 deficiency induces the systemic hyperoxidation of peroxiredoxin in the mouse.
    Biochem Biophys Res Commun
    , 463:1040-1046 (2015) 
  8. Ham SA, Yoo T, Hwang JS, Kang ES, Paek KS, Park C, Kim JH, Do JT, Seo HG.
    Peroxisome proliferator-activated receptor ƒÂ modulates MMP-2 secretion and elastin expression in human dermal fibroblasts exposed to ultraviolet B radiation. 
    J Dermatol Sci. 2014;76(1):44-50. (IF:3.335)
  9. Ham SA, Lee H, Hwang JS, Kang ES, Yoo T, Paek KS, Do JT, Park C, Oh JW, Kim JH, Han CW, Seo HG.
    Activation of Peroxisome Proliferator-Activated Receptor ƒÂ Inhibits Angiotensin II-Induced Activation of Matrix Metalloproteinase-2 in Vascular Smooth Muscle Cells.
    J Vasc Res. 2014;51(3):221-30. (IF:2.443)
  10. Hwang JS, Kim HJ, Kim G, Kang ES, Ham SA, Yoo T, Paek KS, Yabe-Nishimura C, Kim HJ, Seo HG.
    PPARƒÂ reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice by regulating extracellular matrix homeostasis and inflammatory responses.
    Int J Cardiol. 2014;174(1):43-50. (IF:6.175)
  11. Kang ES, Hwang JS, Ham SA, Park MH, Kim GH, Paek KS, Yoo T, Lee WJ, Kang KR, Lee JH, Choi YJ, Seo HG.
    15-Deoxy-Ģ(12,14)-prostaglandin J2 prevents oxidative injury by upregulating the expression of aldose reductase in vascular smooth muscle cells.

    Free Radic Res. 2014;48(2):218-29. (IF: 2.989)
  12. Ham SA*, Kang ES*, Lee H, Hwang JS, Yoo T, Paek KS, Park C, Kim JH, Lim DS, Seo HG.
    PPARƒÂ Inhibits UVB-Induced Secretion of MMP-1 through MKP-7-Mediated Suppression of JNK Signaling.
    J Invest Dermatol. 2013;133(11):2593-600. (IF: 6.372) (*equal contribution)
  13. Kang ES, Ham SA, Hwang JS, Lee CK, Seo HG.
    Effects of Garcinia cambogia extract on the adipogenic differentiation and lipotoxicity.
    Korean J Food Sci An. 2013;33(3):411-6. (IF: 0.253)
  14. Kang ES, Hwang JS, Kim MH, Kim HG, Lee CK, Seo HG.
    Effect of Garcinia cambogia extract-containing dip-sauce for meat on lipid accumulation and body weight reduction in rats fed high-fat diet.
    Korean J Food Sci An. 2013;33(2):276-80. (IF: 0.253)
  15. Hwang JS*, Kang ES*, Ham SA, Yoo T, Lee H, Paek KS, Park C, Kim JH, Lim DS, Seo HG.
    Activation of peroxisome proliferator-activated receptor ƒÁ by rosiglitazone inhibits lipopolysaccharide-induced release of high mobility group box 1.
    Mediators Inflamm. 2012;2012:352807. (IF: 2.417) (*equal contribution)
  16. Kim MY*, Kang ES*, Ham SA*, Hwang JS, Yoo TS, Lee H, Paek KS, Park C, Lee HT, Kim JH, Han CW, Seo HG..
    The PPARƒÂ-mediated inhibition of angiotensin II-induced premature senescence in human endothelial cells is SIRT1-dependent.
    Biochem Pharmacol. 2012;84(12):1627-34. (IF: 4.650) (*equal contribution)
  17. Han CW*, Kang ES*, Ham SA, Woo HJ, Lee JH, Seo HG.
    Antioxidative effects of Alisma orientale extract in palmitate-induced cellular injury.
    Pharm Biol. 2012;50(10):1281-8. (IF: 1.337) (*equal contribution)
  18. Jin H, Ham SA, Kim MY, Woo IS, Kang ES, Hwang JS, Lee KW, Kim HJ, Roh GS, Lim DS, Kang D, Seo HG.
    Activation of peroxisome proliferator-activated receptor-ƒÂ attenuates glutamate-induced neurotoxicity in HT22 mouse hippocampal cells.
    J Neurosci Res. 2012;90(8):1646-53. (IF: 2.729)
  19. Lee H, Ham SA, Kim MY, Kim JH, Paek KS, Kang ES, Kim HJ, Hwang JS, Yoo T, Park C, Kim JH, Lim DS, Han CW, Seo HG.
    ctivation of PPARƒÂ counteracts angiotensin II-induced ROS generation by inhibiting rac1 translocation in vascular smooth muscle cells.
    Free Radic Res. 2012;46(7):912-9. (IF: 2.989)
  20. Ham SA, Hwang JS, Yoo T, Lee H, Kang ES, Park C, Oh JW, Lee HT, Min G, Kim JH, Seo HG.
    Ligand-activated PPARƒÂ inhibits UVB-induced senescence of human keratinocytes via PTEN-mediated inhibition of superoxide production.
    Biochem J. 2012;444(1):27-38. (IF: 4.779)
  21. Kim HJ, Ham SA, Kim MY, Hwang JS, Lee H, Kang ES, Yoo T, Woo IS, Yabe-Nishimura C, Paek KS, Kim JH, Seo HG.
    PPARƒÂ coordinates angiotensin II-induced senescence in vascular smooth muscle cells through PTEN-mediated inhibition of superoxide generation.
    J Biol Chem. 2011;286(52):44585-93. (IF: 4.600)
  22. Woo IS, Jin H, Kang ES, Kim HJ, Lee JH, Chang KC, Park JY, Choi WS, Seo HG.
    TMEM14A inhibits N-(4-hydroxyphenyl)retinamide-induced apoptosis through the stabilization of mitochondrial membrane potential.
    Cancer Lett. 2011;309(2):190-8. (IF: 5.016)
  23. Kim HJ, Ham SA, Paek KS, Hwang JS, Jung SY, Kim MY, Jin H, Kang ES, Woo IS, Kim HJ, Lee JH, Chang KC, Han CW, Seo HG.
    Transcriptional up-regulation of antioxidant genes by PPARƒÂ inhibits angiotensin II-induced premature senescence in vascular smooth muscle cells.
    Biochem Biophys Res Commun. 2011;406(4):564-9. (IF: 2.281)
  24. Kang ES, Iwata K, Ikami K, Ham SA, Kim HJ, Chang KC, Lee JH, Kim JH, Park SB, Kim JH, Yabe-Nishimura C, Seo HG.
    Aldose reductase in keratinocytes attenuates cellular apoptosis and senescence induced by UV radiation.
    Free Radic Biol Med. 2011;50(6):680-8. (IF: 5.710)
  25. Ham SA, Kim HJ, Kim HJ, Kang ES, Eun SY, Kim GH, Park MH, Woo IS, Kim HJ, Chang KC, Lee JH, Seo HG.
    PPARdelta promotes wound healing by upregulating TGF-beta1-dependent or -independent expression of extracellular matrix proteins.
    J Cell Mol Med. 2010;14(6B):1747-59. (IF: 3.698)
  26. Woo IS, Eun SY, Kim HJ, Kang ES, Kim HJ, Lee JH, Chang KC, Kim JH, Hong SC, Seo HG.
    Farnesyl diphosphate synthase attenuates paclitaxel-induced apoptotic cell death in human glioblastoma U87MG cells.
    Neurosci Lett. 2010;474(2):115-20. (IF: 2.055)
  27. Woo IS, Eun SY, Jang HS, Kang ES, Kim GH, Kim HJ, Lee JH, Chang KC, Kim JH, Han CW, Seo HG.
    Identification of ADP-ribosylation factor 4 as a suppressor of N-(4-hydroxyphenyl)retinamide-induced cell death.
    Cancer Lett. 2009;276(1):53-60. (IF: 5.016)
  28. Kang ES, Kim GH, Woo IS, Kim HJ, Eun SY, Ham SA, Jin H, Kim MY, Park MH, Kim HJ, Chang KC, Lee JH, Kim JH, Yabe-Nishimura C, Seo HG.
    Down-regulation of aldose reductase renders J774A.1 cells more susceptible to acrolein- or hydrogen peroxide-induced cell death.
    Free Radic Res. 2008;42(11-12):930-8. (IF: 2.989)
  29. Kang ES, Kim GH, Kim HJ, Woo IS, Ham SA, Jin H, Kim MY, Kim HJ, Lee JH, Chang KC, Seo HG, Hwang JY.
    Nrf2 regulates curcumin-induced aldose reductase expression indirectly via nuclear factor-kappaB.
    Pharmacol Res. 2008;58(1):15-21. (IF: 3.976)
  30. Kang ES, Woo IS, Kim HJ, Eun SY, Paek KS, Kim HJ, Chang KC, Lee JH, Lee HT, Kim JH, Nishinaka T, Yabe-Nishimura C, and Han Geuk Seo.
    Up-regulation of aldose reductase expression mediated by phosphatidylinositol 3-kinase/Akt and Nrf2 is involved in the protective effect of curcumin against oxidative damage.
    Free Radic Biol Med. 2007;43(4):535-45. (IF: 5.710)
  31. Kim HJ, Woo IS, Kang ES, Eun SY, Kim GH, Ham SA, Kim HJ, Lee JH, Chang KC, Kim J-H, Lee HT, Seo HG.
    Phorbol ester potentiates the growth inhibitory effects of troglitazone via up-regulation of PPARgamma in A549 cells.
    Biochem Biophys Res Commun. 2006;349(2):660-7. (IF: 2.281)
  32. Kim HJ, Woo IS, Kang ES, Eun SY, Kim HJ, Lee JH, Chang KC, Kim JH, Seo HG.
    Identification of a truncated alternative splicing variant of human PPARgamma1 that exhibits dominant negative activity.
    Biochem Biophys Res Commun. 2006;347(3):698-706. (IF: 2.281)
  33. Lee YS, Paek KS, Kang ES, Jang HS, Kim HJ, Kang YJ, Kim JH, Lee HT, Lee JH, Chang KC, Nishinaka T, Seo HG.
    Involvement of nuclear factor kappaB in up-regulation of aldose reductase gene expression by 12-O-tetradecanoylphorbol-13-acetate in HeLa cells.
    Int J Biochem Cell Biol. 2005;37(11):2297-309. (IF: 4.240)
  34. Kang ES, Kim HJ, Paek KS, Jang HS, Chang KC, Lee JH, Nishinaka T, Yabe-Nishimura C, Seo HG.
    Phorbol ester up-regulates aldose reductase expression in A549 cells: a potential role for aldose reductase in cell cycle modulation.
    Cell Mol Life Sci. 2005;62(10):1146-55. (IF: 5.856)
  35. Oh HM, Kang YJ, Kim SH, Lee YS, Park MK, Heo JM, Sun JJ, Kim HJ, Kang ES, Kim HJ, Seo HG, Lee JH, Yun-Choi HS, Chang KC.
    Agastache rugosa leaf extract inhibits the iNOS expression in ROS 17/2.8 cells activated with TNF-alpha and IL-1beta.
    Arch Pharm Res. 2005;28(3):305-10. (IF: 1.751)



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